This link is to a page of Biology and Chemistry pick up lines. Warning: They are all funny to a biologist/chemist but some might find them offensive! Example: If I was an endoplasmic reticulum, how would you want me: smooth or rough?
Sigh. For women that are just sick of men hitting on them. A few of these don't need a comeback because they weren't a rude question, but a few are quite annoying and these are great comebacks for them.