Isabella Romola de' Medici 1542–1576 daughter of Cosimo I de' Medici, 1st Grand Duke of Tuscany & Eleonora di Toledo. She married Paolo Giordano I Orsini at 16. She remained in her father's household after marriage, giving her an unusual degree of independence for a woman of her period. After her father’s death, she was murdered w/ the complicity of her husband & brother. A great beauty, she had a lively, high-spirited & impulsive character that was commented on by courtiers.